Antibiotic Resistance in Pseudomonas aeruginosa and Acinetobacter baumannii Species Isolated in the Conakry Region, Guinea
Mamadou Bobo Diallo *
Department of Pharmacy, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Guinea and National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Celestin Guilavogui
Department of Pharmacy, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Guinea.
Moussa CONDE
Department of Pharmacy, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Guinea and National Reference Laboratory for Mycobacteria, Guinea.
Almamy Amara TOURE
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea and Department of Medicine, Public Health Chair, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Guinea.
Jean Sele BAVOGUI
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Fatoumata Binta BALDE
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Josue DELAMOU
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Sekouba KOUROUMA
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Lancinet SANGARE
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Boubane Benoit THIARA
National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
Kaba KOUROUMA
Department of Pharmacy, Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Guinea and National Institute of Public Health, Ministry of Health and Public Hygiene, Conakry, Guinea.
*Author to whom correspondence should be addressed.
Abstract
Introduction: This study aimed to investigate the antibiotic resistance of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated in the Conakry region from 2022 to 2024.
Study Type: This cross-sectional study was conducted from 2022 to 2024 in the Conakry region.
Study Location and Duration: National Institute of Public Health (INSP), Biomar-24 medical biology laboratory, and Donka University Hospital Center, between 2022 and 2024.
Methods: Bacterial identification and antibiotic susceptibility testing were performed using VITEK 2 Compact, following EUCAST guidelines.
Results: Eighty bacterial strains were isolated, of which 57.5% were Acinetobacter baumannii and 42.5% were Pseudomonas aeruginosa. Regarding the origin of the samples, urine samples were the most common at 57.5%, followed by pus (15%) and blood (13.75%). There was high resistance to ticarcillin (43.75%), ceftazidime (32.5%), and piperacillin-tazobactam (31.25%), and low resistance to colistin (5%) and imipenem (7.52%), making them the most effective antibiotics. In addition, there was notable resistance to tobramycin (33.75%), especially in Acinetobacter baumannii.
Conclusion: This study highlights an alarming frequency of resistance. It calls for a strengthening of surveillance policies and better management of antibiotics in Guinea.
Keywords: Resistance, Pseudomonas aeruginosa, Acinetobacter baumannii, Conakry