Hepatitis C Virus Infection among Chronic Renal Failure Patients Pre – Dialysis Therapy in Hodiedah City, Yemen
Mansoor Shueai Al Awfi *
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen and Tihama Foundation for Medical – Pharmaceutical Studies and Research, Hodeidah, Yemen
Mohammed Amood Al-Kamarany
Tihama Foundation for Medical – Pharmaceutical Studies and Research, Hodeidah, Yemen and Department of Pharmacy Practice, Faculty of Clinical Pharmacy, Tropical Medicine Center, Hodeidah University, P.O.Box 3114, Hodeidah, Yemen
Rasheed Mohsen
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen
Mohammed Al Hilali
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen
Waleed Al Khader
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen and Tihama Foundation for Medical – Pharmaceutical Studies and Research, Hodeidah, Yemen
Saleem Al Jafari
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen
Mona Galeb
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen
Hanan Al Amodi
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen
Balqis Moad
Department of Medical Laboratory, Faculty of Medicine and Health Sciences, Hodiedah University, Yemen
*Author to whom correspondence should be addressed.
Abstract
Background: Hepatitis C virus (HCV) infection is a significant problem in hemodialysis patients, which poses difficulty in the management of the patients in the renal dialysis unit.
Objective: This study aimed to detect and determine the prevalence of HCV in renal failure pre- dialysis patients (for the first time) in the renal dialysis center of Hodiedah city, Yemen.
Methods: The demographic data of 278 renal failure patients collected retrospectively for a period of 4 years and eight months from January 2011 to September 2015. All patients screened for HCV antibodies using one-step cassette style anti-HCV device. The positive samples were confirmed by enzyme linked immunosorbent assay (ELISA). The demographic data of patients were recorded namely sex, age, education, residence and occupation.
Results: Out of 278 patients, three cases (1.07%) were found having HCV infection. Out of the three positive patients, two cases (1.18%) were males and one case (0.92%) was female. Two cases of 132 patients (1.54%) were found in the 21- 40 age group and one case of 114 patients (0.88%) found in the 41- 60 age group. No prevalence was observed in the age group of < 20 years and > 60 years. HCV was detected in one case (0.79%) of 127 urban residence patients and in 2 cases (1.32%) of 151 rural residence patients. The prevalence of HCV was showed among non-educated subjects (two cases = 1.54%) and in educated subjects (one case = 0.68%). Out of 252 non-occupant patients, three cases (1.19%) were found to be positive HCV antibodies. No prevalence was observed in 26 occupant patients.
Conclusion: In conclusion, pre dialysis screening for HCV was an effective strategy taken to ensure containment of hospital acquired infection (HAI) by isolation of patients in certain machine.
Keywords: Renal, chronic, acute, failure, HCV