Antibiotic Susceptibility of Neisseria gonorrhoeae in Bacolod City, Philippines
Alain C. Juayang *
Clinical Laboratory, Dr. Pablo O. Torre Memorial Hospital, Philippines. & Medical Technology Program, Colegio San Agustin – Bacolod, Philippines.
Joseph Peter T. Lim
Medical Technology Program, Colegio San Agustin – Bacolod, Philippines.
Michael Angelo D. Acosido
Medical Technology Program, Colegio San Agustin – Bacolod, Philippines.
Dominador G. Maestral Jr
Medical Technology Program, Colegio San Agustin – Bacolod, Philippines.
Christine T. Gallega
Clinical Laboratory, Dr. Pablo O. Torre Memorial Hospital, Philippines.
*Author to whom correspondence should be addressed.
Abstract
Resistance of Neisseria gonorrhoeae against clinically recommended antibiotics continues to rise globally. This retrospective study aimed to describe the antimicrobial resistance and resistance trend of N. gonorrhoeae in Bacolod City from February 2010 to January 2015. A total of 99 isolates (97 males and 2 females) from ages 15 to 65 were included in the study. The highest incidence was observed between 25 - 29 age bracket. Resistance rate against the tested antibiotics were as follows: penicillin (100%), ciprofloxacin (75.3%), tetracycline (69%), spectinomycin (8%), cefixime (0%) and ceftriaxone (0%). Production of beta-lactamase was also found in all isolates; while presumed plasmid mediated tetracycline resistance was found in 34 isolates. Resistance to ciprofloxacin and tetracycline were also seen to be increasing during the five year study, but resistance to third generation cephalosporins, namely cefexime and ceftriaxone remains unchanged.
Keywords: Neisseria gonorrhoeae, antimicrobial resistance, bacolod city