Molecular Detection of Torque Teno Virus among HIV Seropositive Patients in Khartoum, Sudan
Ibrahim A. Almoshrf
Department of Microbiology, Faculty of Medical Laboratories, Al Neelain University, Khartoum, Sudan.
Abdel Rahim M. El Hussein
Department of Virology Central Laboratory, The Ministry of Higher Education and Scientific Research, Khartoum, Sudan.
Isam M. Elkhidir
Department of Microbiology and Parasitology, University of Khartoum, Khartoum, Sudan.
Khalid A. Enan *
Department of Virology Central Laboratory, The Ministry of Higher Education and Scientific Research, Khartoum, Sudan.
*Author to whom correspondence should be addressed.
Abstract
Background: Torque Teno Virus (TTV) is a newly discovered non- enveloped, single-stranded DNA virus of high genotypic variability, frequently detected in patients with acute or chronic hepatitis with non A-G etiology.
Objective: This study was carried out to look for the presence of TTV among HIV seropositive patients in Khartoum State, Sudan using polymerase chain reaction (PCR) technique.
Methods: A total of 44 blood samples from HIV positive patients were tested for the presence of TTV DNA by polymer as chain reaction (PCR) using primers from UN translated (UTR) region.
Results: During the study period, 44 HIV positive patients (16male and 28female) were enrolled. Out of these TTV viri was detected in 10(22.7%) HIV positive samples.
Conclusion: The rate of TTV infection among Sudanese HIV patients was (22 %( 10/44).
Keywords: Torque Teno virus (TTV), human immunodeficiency virus (HIV), polymerase chain reaction (PCR), UN translated (UTR)