Antibacterial Potential of Different Parts of Aerva lanata (L.) Against Some Selected Clinical Isolates from Urinary Tract Infections
Ramalingam Vidhya
Department of Biochemistry, Government Arts College (Autonomous), Kumbakonam-612001, Tamilnadu, India and Department of Biochemistry, Dharmapuram Gnanambigai Government Arts College for Women, Mayiladuthurai-609 001, Tamilnadu, India.
Rajangam Udayakumar *
Department of Biochemistry, Government Arts College (Autonomous), Kumbakonam-612001, Tamilnadu, India.
*Author to whom correspondence should be addressed.
Abstract
Aims: To investigate the antibacterial activity of different parts of Aerva lanata against Staphylococcus saprophyticus, Streptococcus agalactiae, Acinetobacter baumannii, Xanthomonus citri, Klebsiella pneumoniae and Proteus vulgaris.
Study Design: An experimental study.
Place and Duration of Study: This study was carried out in the Department Laboratory, Government Arts College (Autonomous), Kumbakonam-612 001, Tamilnadu, India, between November 2013 and April 2014.
Methodology: The different solvents like acetone, aqueous, benzene and ethyl acetate were used for the preparation of extracts. The antibacterial activity of the different solvent extracts of root, flower and leaf of A. lanata was determined by agar well diffusion method. Different concentration of extracts 5 mg / 25 µl, 10 mg / 50 µl, 15 mg / 75 µl and 20 mg / 100 µl were tested against selected microorganisms
Results: All extracts have different level of antibacterial activity and it was compared with standard drug streptomycin. The maximum level of bacterial growth inhibition was seen in root extracts of A. lanata.
Conclusion: The present investigation clearly indicates that the different solvent extracts of root, flower and leaf of A. lanata exhibited broad-spectrum antibacterial activity. The ethyl acetate extract of root have higher activity when compared to flower and leaf extracts.
Keywords: Aerva lanata, antibacterial activity, acetone, aqueous, benzene, ethyl acetate, well diffusion method